Products for Research Use Only

Tubercidin

CAT: 0013-GTR19168368-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168368-01Size:5 mg
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Description
Tubercidin (Sparsomycin A) is a nucleoside antibiotic analog of adenosine that incorporates into nucleic acids to inhibit DNA and RNA polymerases, blocking replication and transcription. It is utilized in biochemical research for its antiviral and antifungal properties in both in vitro and cell-based studies.
CAS Number
69-33-0
Product Name Alternative
Sparsomycin A, Tubercidin, RNASynthesis, RNA Synthesis, DNASynthesis, DNA/RNA Synthesis, DNA Synthesis, Bacterial, Antibiotic, 7-Deazaadenosine, inhibit, Influenza Virus, InfluenzaVirus, Inhibitor
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology
Purity
98.66% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:55 mg/mL (206.57 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.51 mM)
Smiles
Nc1ncnc2n (ccc12) [C@@H]1O[C@H] (CO) [C@@H] (O) [C@H]1O
Molecular Formula
C11H14N4O4
Molecular Weight
266.25
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Tubercidin

Tubercidin is an N-glycosylpyrrolopyrimidine that is adenosine in which the in the 5-membered ring that is not attached to the ribose moiety is replaced by a carbon. Tubercidin is produced in the culture broth of Streptomyces tubericidus. It has a role as an antimetabolite, an antineoplastic agent and a bacterial metabolite. It is a ribonucleoside, a N-glycosylpyrrolopyrimidine and an antibiotic antifungal agent.

CAS Number69-33-0
PubChem CID6245
IUPAC Name(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Molecular FormulaC11H14N4O4
Molecular Weight266.25
XLogP-1.3
Topological Polar Surface Area127
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Heavy Atom Count19
Formal Charge0
Complexity334
SMILES
C1=CN(C2=NC=NC(=C21)N)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
InChI
InChI=1S/C11H14N4O4/c12-9-5-1-2-15(10(5)14-4-13-9)11-8(18)7(17)6(3-16)19-11/h1-2,4,6-8,11,16-18H,3H2,(H2,12,13,14)/t6-,7-,8-,11-/m1/s1
InChIKey
HDZZVAMISRMYHH-KCGFPETGSA-N
Chemical Structure
2D Structure
2D structure of Tubercidin
CAS: 69-33-0
CID: 6245
Formula: C11H14N4O4
MW: 266.25
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight266.25
XLogP3-1.3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Exact Mass266.10150494
Monoisotopic Mass266.10150494
Topological Polar Surface Area127 Ų
Heavy Atom Count19
Formal Charge0
Complexity334
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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