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SR-8278

CAT: 0013-GTR19167355-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167355-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SR8278 is a potent REV-ERBα antagonist with an EC50 of 0.47 μM, effectively inhibiting receptor activation by agonists like GSK4112. This tool compound is widely used in circadian rhythm, metabolism, and inflammation research, supporting both in vitro mechanistic studies and in vivo pharmacological investigations.
CAS Number
1254944-66-5
Product Name Alternative
SR8278, SR-8278, SR 8278, REV-ERB, REV-ERBα, inhibit, neurosurgery, metabolism, Inhibitor, Alzheimer's disease, biological rhythm, Duchenne muscular dystrophy
Field of Research
Cell Biology
Purity
>98%
Bioactivity
RevErb a antagonist
Form
Powder
Solubility
Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 35 mg/ml)
Smiles
CCOC (=O) C1Cc2ccccc2CN1C (=O) c1ccc (SC) s1
Molecular Formula
C18H19NO3S2
Molecular Weight
361.49
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1,2,3,4-Tetrahydro-2-[[5- (methylthio) -2-thienyl]carbonyl]-3-isoquinolinecarboxylic acid ethyl ester

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