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Macozinone

CAT: 0013-GTR19163367-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19163367-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Macozinone (PBTZ-169, PBTZ169) is a potent, second-generation antituberculosis agent that inhibits DprE1 and displays nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro; PBTZ169 is less cytotoxic than BTZ043 and shows significantly better efficacy at lower concentrations in the murine model of chronic TB, inhibits DprE1 more efficiently than BTZ043.Bacterial Infection Phase 2 Clinical (In Vitro) :Macozinone (PBTZ169) is highly potent against M. tuberculosis in vitro, ex vivo, and in vivo.
CAS Number
1377239-83-2
Product Name Alternative
PBTZ169 | PBTZ-169
Purity
>98% (HPLC)
Solubility
DMSO: 6.4 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C1N=C (N2CCN (CC3CCCCC3) CC2) SC4=C ([N+] ([O-]) =O) C=C (C (F) (F) F) C=C14
Molecular Formula
C20H23F3N4O3S
Molecular Weight
456.484
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-[4- (cyclohexylmethyl) piperazin-1-yl]-8-nitro-6- (trifluoromethyl) -4H-1,3-benzothiazin-4-one

Alternative Products

CatalogName
HY-12903-01Macozinone
A21488-50Macozinone 50mg
A21488-10Macozinone 10mg
HY-12903R-01Macozinone (Standard)
A21488-200Macozinone 200mg
A21488-100Macozinone 100mg
A21488-25Macozinone 25mg
A21488-5Macozinone 5mg

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