Products for Research Use Only
RegisterLogin

LDC1267

CAT: 0013-GTR19160547-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19160547-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LDC1267 is a potent and selective TAM kinase inhibitor. LDC1267 displays lower activity against Met, Aurora B, Lck, Src, and CDK8. LDC1267 markedly reduced murine mammary cancer and melanoma metastases dependent on NK cells. The TAM tyrosine kinase receptors Tyro3, Axl and Mer (also known as Mertk) were identified as ubiquitylation substrates for Cbl-b. Treatment of wild-type NK cells with a newly developed small molecule TAM kinase inhibitor conferred therapeutic potential, efficiently enhancing anti-metastatic NK cell activity in vivo.
CAS Number
1361030-48-9
Product Name Alternative
LDC1267 | LDC-1267 | LDC 1267
Purity
>98% (HPLC)
Solubility
DMSO : 50 mg/mL. 89.20 mM; H2O : < 0.1 mg/mL
Smiles
C1 (c (cc2c (c1) c (ccn2) Oc1ccc (cc1F) NC (=O) c1nn (cc1OCC) c1ccc (cc1C) F) OC) OC
Molecular Formula
C30H26F2N4O5
Molecular Weight
560.55
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N-[4-[ (6,7-dimethoxy-4-quinolyl) oxy]-3-fluoro-phenyl]-4-ethoxy-1- (4-fluoro-2-methyl-phenyl) pyrazole-3-carboxamide

Related Products

CatalogName
GTR19189016LDC4297
GTR19160511-01LDC4297
GTR19212819LDC4297 hydrochloride

Alternative Products

CatalogName
C12834-10mM/1mLLDC1267
A13003-25LDC1267 25mg
A13003-100LDC1267 100mg
A13003-50LDC1267 50mg
A13003-5LDC1267 5mg
A13003-2LDC1267 2mg
A13003-10LDC1267 10mg

Popular Products