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BAR 501

CAT: 0013-GTR19160470-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160470-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAR-501 is a selective GPBAR1 agonist devoid of any FXR agonistic activity. BAR501 effectively reduced hepatic perfusion pressure and counteracted the vasoconstriction activity of norepinephrine. BAR501 rescues from endothelial dysfunction in rodent models of portal hypertension by exerting genomic and non-genomic effects on CSE, eNOS and ET-1 in liver sinusoidal cells.
CAS Number
1632118-69-4
Product Name Alternative
BAR-501 | BAR 501 | BAR501
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 50 mg/mL. 122.96 mM
Smiles
CC[C@H]1[C@@H]2C[C@@H] (CC[C@@]2 ([C@H]2CC[C@]3 ([C@H] ([C@@H]2[C@H]1O) CC[C@@H]3[C@H] (C) CCCO) C) C) O
Molecular Formula
C26H46O3
Molecular Weight
406.65
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(3R,5S,6S,7S,8S,9S,10S,13R,14S,17R) -6-ethyl-17- ((R) -5-hydroxypentan-2-yl) -10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

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