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O4I2

CAT: 0013-GTR19160460-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160460-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
O4I2 is a potent inducers of Oct3/4. O4I2 showed high activity in enforcing Oct3/4 expression. O4I2 is a new class of small molecules suitable for iPSC generation. The octamer-binding transcription factor 4 (Oct3/4) is a master gene in the transcriptional regulatory network of pluripotent cells. Repression of Oct3/4 in embryonic stem cells (ESCs) is associated with cell differentiation and loss of pluripotency, whereas forced overexpression in cooperation with other transcriptional factors, such as Nanog, Sox2, and Lin28, can reprogram somatic cells back into pluripotent cells, termed induced pluripotent stem cells (iPSCs) .
CAS Number
165682-93-9
Product Name Alternative
O4I2 | O-4I2 | O4I-2
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 42 mg/mL; 148.54 mM
Smiles
CCOC (=O) c1csc (n1) Nc1ccc (cc1) Cl
Molecular Formula
C12H11ClN2O2S
Molecular Weight
282.75
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Ethyl 2- ((4-chlorophenyl) amino) thiazole-4-carboxylate

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