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Emapunil

CAT: 0013-GTR19160386-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19160386-01Size:1 g
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Description
Emapunil is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. (In Vivo) :Emapunil (AC-5216, 0.1-3, 0.003-0.01 and 0.01-0.3 mg/kg, p.o.) produces anti-anxiety effects in the Vogel-type conflict test in rats, and in the light/dark box and social interaction tests in mice.Emapunil (AC-5216, 3-30 mg/kg, p.o.) reduces the immobility time, and this effect was blocked by PK11195.Emapunil (AC-5216, 1-100 mg/kg, p.o.) produces no distinct change in the rat electroencephalogram.Emapunil (AC-5216, 0.3 and 1 mg/kg, i.g.) causes significant suppression of the enhanced anxiety and contextual fear induced in post-TDS rats.Emapunil (AC-5216, 0.3 and 1 mg/kg, i.g.) alleviates the enhanced anxiety and fear response in a time-dependent sensitization (TDS) procedure, a rat PTSD animal model.Emapunil (AC-5216, 0.3 and 1 mg/kg, i.g.) reverses the increased plasma glucose (PG) and decreased insulin (INS) in HFD-STZ rats.
CAS Number
226954-04-7
Product Name Alternative
AC-5216 | XBD-173
Purity
>98% (HPLC)
Solubility
DMSO : 33.33 mg/mL 83.02 mM
Smiles
CCN (Cc1ccccc1) C (=O) Cn1c2nc (ncc2n (c1=O) C) c1ccccc1
Molecular Formula
C23H23N5O2
Molecular Weight
401.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
HY-15527-01Emapunil
HY-15527R-01Emapunil (Standard)
C08700-5mgEmapunil (AC 5216)
MBS387635-01AC-5216 (Emapunil)
A13138-200AC-5216 (Emapunil) 200mg
A13138-5AC-5216 (Emapunil) 5mg
A13138-1AC-5216 (Emapunil) 1mg
A13138-100AC-5216 (Emapunil) 100mg
228028Emapunil (AC-5216, XBD-173)
A13138-10mM-DAC-5216 (Emapunil) 10mM * 1mL in DMSO

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