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NIH-12848

CAT: 0013-GTR19160150-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19160150-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ with an IC50 of approximately 1 μM but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 is a potentially powerful tool for exploring the cell physiology of PI5P4Ks.
CAS Number
959551-10-1
Product Name Alternative
NIH-12848 | NCGC00012848-02.
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 28 mg/mL; 72.65 mM
Smiles
FC (F) (F) c1ccccc1c1nc2ccccc2c (NCc2cccs2) n1
Molecular Formula
C20H14F3N3S
Molecular Weight
385.41
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (thiophen-2-ylmethyl) -2- (2- (trifluoromethyl) phenyl) quinazolin-4-amine

Chemical Information

N-[(thiophen-2-yl)methyl]-2-[2-(trifluoromethyl)phenyl]quinazolin-4-amine
CAS Number959551-10-1
PubChem CID3235425
IUPAC NameN-(thiophen-2-ylmethyl)-2-[2-(trifluoromethyl)phenyl]quinazolin-4-amine
Molecular FormulaC20H14F3N3S
Molecular Weight385.4
XLogP5.6
Topological Polar Surface Area66.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Heavy Atom Count27
Formal Charge0
Complexity490
SMILES
C1=CC=C(C(=C1)C2=NC3=CC=CC=C3C(=N2)NCC4=CC=CS4)C(F)(F)F
InChI
InChI=1S/C20H14F3N3S/c21-20(22,23)16-9-3-1-7-14(16)19-25-17-10-4-2-8-15(17)18(26-19)24-12-13-6-5-11-27-13/h1-11H,12H2,(H,24,25,26)
InChIKey
QBDAEJRHUCSSPR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-[(thiophen-2-yl)methyl]-2-[2-(trifluoromethyl)phenyl]quinazolin-4-amine
CAS: 959551-10-1
CID: 3235425
Formula: C20H14F3N3S
MW: 385.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight385.4
XLogP35.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count4
Exact Mass385.08605312
Monoisotopic Mass385.08605312
Topological Polar Surface Area66.1 Ų
Heavy Atom Count27
Formal Charge0
Complexity490
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
530601NIH-12848
A20476-10NIH-12848 10mg
A20476-2NIH-12848 2mg
A20476-50NIH-12848 50mg
A20476-25NIH-12848 25mg
A20476-200NIH-12848 200mg
A20476-100NIH-12848 100mg
A20476-5NIH-12848 5mg

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