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Ginsenoside Rg5

CAT: 0013-GTR19159949-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159949-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. Ginsenoside Rg5 can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR) -4 on macrophages. Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasculature. Ginsenoside Rg5 blocks cell cycle of SK-HEP-1 cells at the Gl/S transition phase by down-regulating cyclin E-dependent kinase activity and that the down-regulation of cyclin E-dependent kinase activity is caused mainly by induced CDK2 inhibitor, p21Cip/WAF1 and decreased levels of cyclin E.
CAS Number
186763-78-0
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (65.19 mM)
Smiles
CC (=CCC=C (C) C1CCC2 (C1C (CC3C2 (CCC4C3 (CCC (C4 (C) C) OC5C (C (C (C (O5) CO) O) O) OC6C (C (C (C (O6) CO) O) O) O) C) C) O) C) C
Molecular Formula
C42H70O12
Molecular Weight
767.01
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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