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Ginsenoside F1

CAT: 0013-GTR19162096-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19162096-01Size:100 mg
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Description
Ginsenoside F1, an enzymatically modified derivative of ginsenoside Rg1, protection from ultraviolet-B-induced apoptosis is tightly correlated with ginsenoside-F1-mediated inhibition of ultraviolet-B-induced downregulation of Bcl-2 and Brn-3a expression. Ginsenoside F1 exhibited competitive inhibition of the activity of CYP3A4 with Ki values of 57.7 ± 9.6 μM and 67.8 ± 16.2 μM, respectively. Ginsenoside F1 exhibited a weaker inhibition of the activity of CYP2D6.
CAS Number
53963-43-2
Purity
>98% (HPLC)
Solubility
Soluble in Pyridine, Methanol, Ethanol, etc.
Smiles
CC (=CCC[C@@] (C) ([C@H]1CC[C@@]2 ([C@@H]1[C@@H] (C[C@H]3[C@]2 (C[C@@H] ([C@@H]4[C@@]3 (CC[C@@H] (C4 (C) C) O) C) O) C) O) C) O[C@H]5[C@@H] ([C@H] ([C@@H] ([C@H] (O5) CO) O) O) O) C
Molecular Formula
C36H62O9
Molecular Weight
638.88
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Chemical Information

Ginsenoside F1

Ginsenoside F1 is a ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 20 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. It has a role as an apoptosis inhibitor and a plant metabolite. It is a 3beta-hydroxy-4,4-dimethylsteroid, a beta-D-glucoside, a tetracyclic triterpenoid, a 3beta-hydroxy steroid, a 12beta-hydroxy steroid, a 6alpha-hydroxy steroid and a ginsenoside. It derives from a hydride of a dammarane.

CAS Number53963-43-2
PubChem CID9809542
IUPAC Name(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[(2S)-6-methyl-2-[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,6,12-trihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-5-en-2-yl]oxyoxane-3,4,5-triol
Molecular FormulaC36H62O9
Molecular Weight638.9
XLogP4.3
Topological Polar Surface Area160
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count9
Rotatable Bond Count7
Heavy Atom Count45
Formal Charge0
Complexity1110
SMILES
CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(C[C@@H]([C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O)C)O)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C
InChI
InChI=1S/C36H62O9/c1-19(2)10-9-13-36(8,45-31-29(43)28(42)27(41)23(18-37)44-31)20-11-15-34(6)26(20)21(38)16-24-33(5)14-12-25(40)32(3,4)30(33)22(39)17-35(24,34)7/h10,20-31,37-43H,9,11-18H2,1-8H3/t20-,21+,22-,23+,24+,25-,26-,27+,28-,29+,30-,31-,33+,34+,35+,36-/m0/s1
InChIKey
XNGXWSFSJIQMNC-FIYORUNESA-N
Chemical Structure
2D Structure
2D structure of Ginsenoside F1
CAS: 53963-43-2
CID: 9809542
Formula: C36H62O9
MW: 638.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight638.9
XLogP34.3
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count9
Rotatable Bond Count7
Exact Mass638.43938355
Monoisotopic Mass638.43938355
Topological Polar Surface Area160 Ų
Heavy Atom Count45
Formal Charge0
Complexity1110
Isotope Atom Count0
Defined Atom Stereocenter Count16
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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GTR19269460Ginsenoside Ra1
GTR19261157Ginsenoside Ro
GTR19183688-01Ginsenoside F4

Alternative Products

CatalogName
OG31930-01Ginsenoside Rk1 - Ginsenoside Rk1:Ginsenoside Rz1 (5:2)
300355Ginsenoside Rg3 (20 (s) -Ginsenoside Rg3)
300354Ginsenoside Rg2 (20 (s) -Ginsenoside Rg2)
CS-BS-00118Ginsenoside F1
IDA45941-01Ginsenoside Ra1
ZKA25028-01Ginsenoside rc
OG31929-01Ginsenoside Rk2
OG31928-01Ginsenoside Rh4
MDA73367-01Ginsenoside RS1
TB0648Ginsenoside F3

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