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Neferine

CAT: 0013-GTR19159850-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159850-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Neferine has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. Neferine can be helpful to increase the efficacy of DOX and to achieve anticancer synergism by curbing the toxicity. Neferine inhibited high glucose-induced endothelial apoptosis via blocking ROS/Akt/NF-κB pathway, which provides the evidence for using Neferine to treat diabetic vasculopathy. Neferine induced apoptosis in a dose-dependent manner with the hypergeneration of reactive oxygen species, activation of MAPKs, lipid peroxidation, depletion of cellular antioxidant pool, loss of mitochondrial membrane potential, and intracellular calcium accumulation.
CAS Number
2292-16-2
Product Name Alternative
(-) -Neferine
Purity
>98% (HPLC)
Solubility
DMSO : 62 mg/mL 99.24 mM
Smiles
CN1CCC2=CC (=C (C=C2C1CC3=CC=C (C=C3) OC) OC4=C (C=CC (=C4) CC5C6=CC (=C (C=C6CCN5C) OC) OC) O) OC
Molecular Formula
C38H44N2O6
Molecular Weight
624.77
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
FN65588Neferine
HY-N0441RNeferine (Standard)
A14743-10Neferine 10mg
A14743-50Neferine 50mg
A14743-25Neferine 25mg
A14743-100Neferine 100mg
A14743-5Neferine 5mg
AR-N01235-01Biotinylated Neferine
TRC-N389205-25MGO-Biotinyl Neferine
A14743-10mM-DNeferine 10mM * 1mL in DMSO

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