Products for Research Use Only

Dimethylacrylshikonin

CAT: 0013-GTR19159820-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159820-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dimethylacrylshikonin is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significantly suppressed tumor growth of the HCT-116 xenograft. (b) Dimethylacrylshikonin significantly suppressed the growth of H (22) transplantable hepatoma, and induced the activation of caspase-3 . (c) Dimethylacrylshikonin inhibited growth of gastric cancer SGC-791 cells by inducing ERK signaling pathway. Dimethylacrylshikonin inhibits the proliferation of MCF-7 cells in vitro by inducing apoptosis through the downregulation of Bcl-2, upregulation of Bax and partial inactivation of the NF-κB pathway.
CAS Number
24502-79-2
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 12.5 mg/mL (33.75 mM)
Smiles
CC (=CCC (C1=CC (=O) C2=C (C=CC (=C2C1=O) O) O) OC (=O) C=C (C) C) C
Molecular Formula
C21H22O6
Molecular Weight
370.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.