Products for Research Use Only

Pristimerin

CAT: 0013-GTR19159731-01Size: 1 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19159731-01Size:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Pristimerin has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell characteristics and EMT in cancer cells. Pristimerin down-regulates the expression of pro-inflammatory mediators through blocking of NF-κB activation by inhibiting interconnected ROS/IKK/NF-κB signaling pathways, can effectively inhibit both arthritic inflammation and cartilage and bone damage in the joints.
CAS Number
1258-84-0
Product Name Alternative
Pristimerin | Celastrol-methylether | UNII-28ZK7PR57S
Purity
>98% (HPLC)
Solubility
DMSO : 20 mg/mL 43.04 mM; H2O : < 0.1 mg/mL
Smiles
CC1=C (C (=O) C=C2C1=CC=C3C2 (CCC4 (C3 (CCC5 (C4CC (CC5) (C) C (=O) OC) C) C) C) C) O
Molecular Formula
C30H40O4
Molecular Weight
464.64
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Methyl (2S,4aS,6aR,12bR,14aR,14bR) -10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylate