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Cimifugin

CAT: 0013-GTR19159532-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159532-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cimifugin inhibits NO production induced by lipopolysaccharide in macrophage cell line RAW 264.7 and for 1, 1-diphenyl-2-picrylhydrazyl free-radical scavenging activity in cell-free bioassay system. (In Vitro) :The effect of Cimifugin (Cimitin) on TSLP decreases significantly when expression of CLDN1 is interfered with siRNA and this implied Cimifugin inhibits initiative cytokines through restoring TJs. (In Vivo) :Cimifugin (Cimitin; 12.5 or 50 mg/kg/day; intragastrically; 2 days) significantly inhibits TSLP and IL-33 in the initial stage of Mice are sensitized and challenged with FITC to establish type 2 atopic dermatitis (AD) model. Simultaneously, Cimifugin reduces the separated gap among the epithelial cells and increased the expression of TJs.
CAS Number
37921-38-3
Product Name Alternative
Cimitin
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 3.1 mg/mL; 10.12 mM
Smiles
CC (C) ([C@@H]1Cc2c (O1) cc1c (c2OC) c (=O) cc (o1) CO) O
Molecular Formula
C16H18O6
Molecular Weight
306.3
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

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T3383-01Cimifugin
HY-N0634R-01Cimifugin (Standard)
300076Cimifugin discontinued. See 269510
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TN1496Cimifugin 4'-O-β-D-glucopyranoside
371282Cimifugin 4'-O-β-D-glucopyranoside discontinued
MC74555-01Cimifugin 4'-O-b-D-glucopyranoside

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