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P-Hydroxy-cinnamic acid

CAT: 0013-GTR19159447-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19159447-01Size:1 g
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Description
P-Hydroxycinnamic acid can inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively. (In Vitro) :p-Hydroxycinnamic acid (p-Coumaric acid), is a ubiquitous plant metabolite with antioxidant and anti-inflammatory properties. p-Hydroxycinnamic acid (500 μM and 1 mM) reduces ADP-induced platelet aggregation (55 2 (SE 4 01) % and 35 6 (SE 2 35) % relative to basal level, respectively) . p-Hydroxycinnamic acid is able to modify platelet function, a shear-inducing device that simulates primary haemostasis. p-Hydroxycinnamic acid interferes also with arachidonic acid cascade, reducing thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation (IC50 371 and 126 μM, respectively) .
CAS Number
7400-08-0
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL; 609.16 mM
Smiles
OC (=O) \C=C\c1ccc (O) cc1
Molecular Formula
C9H8O3
Molecular Weight
164.16
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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