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Linarin

CAT: 0013-GTR19159203-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159203-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Linarin (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediated apoptotic pathways. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.
CAS Number
480-36-4
Product Name Alternative
Linarin
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (421.91 mM)
Smiles
CC1C (C (C (C (O1) OCC2C (C (C (C (O2) OC3=CC (=C4C (=C3) OC (=CC4=O) C5=CC=C (C=C5) OC) O) O) O) O) O) O) O
Molecular Formula
C28H32O14
Molecular Weight
592.55
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
7- ((6-O- (6-Deoxy-alpha-L-mannopyranosyl) -beta-D-glucopyranosyl) oxy) -5-hydroxy-2- (4-methoxyphenyl) -4H-benzopyran-4-one

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