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Olprinone

CAT: 0013-GTR19158895-06Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19158895-06Size:10 mg
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Description
Olprinone (Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor.Olprinone has been reported to improve microcirculation and attenuate inflammation. Olprinone is often used to increase cardiac output after cardiopulmonary bypass (CPB) . (In Vivo) :Olprinone (Loprinone) Hydrochloride (0.2 mg/kg; i.p.) modulates the inflammation associated with myocardial ischemia-reperfusion injury in rats.
CAS Number
106730-54-5
Product Name Alternative
Loprinone
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO:10mM
Smiles
Cc1[nH]c (=O) c (cc1-c1ccc2nccn2c1) C#N
Molecular Formula
C14H10N4O
Molecular Weight
250.26
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Chemical Information

Olprinone

Olprinone is a member of bipyridines.

CAS Number106730-54-5
PubChem CID4593
IUPAC Name5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile
Molecular FormulaC14H10N4O
Molecular Weight250.25
XLogP1.5
Topological Polar Surface Area70.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count19
Formal Charge0
Complexity525
SMILES
CC1=C(C=C(C(=O)N1)C#N)C2=CN3C=CN=C3C=C2
InChI
InChI=1S/C14H10N4O/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10/h2-6,8H,1H3,(H,17,19)
InChIKey
JPAWFIIYTJQOKW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Olprinone
CAS: 106730-54-5
CID: 4593
Formula: C14H10N4O
MW: 250.25
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight250.25
XLogP31.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass250.08546096
Monoisotopic Mass250.08546096
Topological Polar Surface Area70.2 Ų
Heavy Atom Count19
Formal Charge0
Complexity525
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA8207-100Olprinone
A3683-25Olprinone Hydrochloride
HY-14254AROlprinone (Standard)
A21869-50Olprinone 50mg
HY-14254-01Olprinone (Hydrochloride)
A21869-200Olprinone 200mg

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