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Propiverine hydrochloride

CAT: 0013-GTR19158854-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19158854-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB) . (In Vitro) :Propiverine (10-3000 nM) inhibits the speci c binding of [3H]NMS, with Kis of 339, 193 and 497 nM in the bladder, submaxillary gland and heart of mice respectively. (In Vivo) :Propiverine (0.5 mg/day; p.o. once daily for 2 weeks) significantly increases UBP and LPP during passive intravesical pressure elevation, and also increases plasma norepinephrine and epinephrine levelsin rats.Propiverine (0.01-1 mg/kg; i.v.) decreases the UBP and totally suppresses the sneeze reflex at the dose of 1 mg/kg in vivo.
CAS Number
54556-98-8
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO:198 mM
Smiles
Cl.CCCOC (C (=O) OC1CCN (C) CC1) (c1ccccc1) c1ccccc1
Molecular Formula
C23H30ClNO3
Molecular Weight
403.94
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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