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Hexamethylene amiloride

CAT: 0013-GTR19158552-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19158552-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 μM) . It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013-2.4 μM for various NHE isoforms. HMA also blocks ASIC3 channels by 51% at 20 μM.
CAS Number
1428-95-1
Product Name Alternative
Hexamethylene amiloride | HMA
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (320.75 mM)
Smiles
NC (=N) NC (=O) C1=C (N) N=C (N2CCCCCC2) C (Cl) =N1
Molecular Formula
C12H18ClN7O
Molecular Weight
311.77
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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