Hexamethylene amiloride

• Description :

  HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 µM) . It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013-2.4 µM for various NHE isoforms.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  311.77

• Molecular Formula :

  C12H18ClN7O

• Notes :

  Research use only, not for human use.

• Receptor :

  NHE exchangers| TRPA1| ASIC3| P2X7

• CAS Number :

  1428-95-1