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BAR502

CAT: 0013-GTR19157982-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157982-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAR502 is a truncated side chain alcohol with both substituents on ring B in α-configuration. At the concentration of 10 μM, BAR502 fails to transactivate GR, PPARγ, and LXR, respectively, but it transactivates the nuclear receptor PXR. BAR502 is able to induce the expression of pro-glucagon mRNA in GLUTAg cells, an intestinal endocrine cell line, as well as to increase cAMP concentrations in THP-1 cells. BAR502 induces the expression of OSTα, BSEP, and SHP in HepG2 cells. BAR502 shows a very potent activity in the recruitment of SRC-1 coactivator and high affinity to FXR.
CAS Number
1612191-86-2
Purity
>98% (HPLC)
Solubility
Ethanol : 100 mg/mL (254.70 mM; Need ultrasonic) ; DMF : 50 mg/mL (127.35 mM; Need ultrasonic)
Smiles
C[C@H] (CCO) [C@@]1 ([H]) CC[C@@]2 ([H]) [C@]3 ([H]) [C@H] (O) [C@H] (CC) [C@]4 ([H]) C[C@H] (O) CC[C@]4 (C) [C@@]3 ([H]) CC[C@@]21C
Molecular Formula
C??H??O?
Molecular Weight
392.62
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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Alternative Products

CatalogName
BA3665-25BAR502
A20433-10BAR502 10mg
A20433-5BAR502 5mg
A20433-200BAR502 200mg
A20433-100BAR502 100mg
A20433-50BAR502 50mg
A20433-25BAR502 25mg
A20433-1BAR502 1mg

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