Products for Research Use Only
RegisterLogin

Clobenpropit dihydrobromide

CAT: 0013-GTR19157937-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19157937-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR, pEC50 of 8.07) Clobenpropit inhibited cell migration and increased apoptosis of pancreatic cancer cells in combination with gemcitabine. Clobenpropit up-regulated E-cadherin, but down-regulated vimentin and matrix metalloproteinase 9 in real-time polymerase chain reaction. Clobenpropit inhibited tumor growth (gemcitabine 294 46 mg vs combination 154 54 mg, P = 0.02) and enhanced apoptosis in combination with gemcitabine (control 2.5%, gemcitabine 25.8%, clobenpropit 9.7% and combination 40.9%, P = 0.001) by up-regulation of E-cadherin and down-regulation of Zeb1 in Panc-1 xenograft mouse.
CAS Number
145231-35-2
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 125 mg/mL (265.59 mM)
Smiles
Br.Br.Clc1ccc (CNC (=N) SCCCc2cnc[nH]2) cc1
Molecular Formula
C14H19Br2ClN4S
Molecular Weight
470.7
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Related Products

CatalogName
GTR19203135-01Clobenpropit 2HBr
GTR19201227-01Impentamine dihydrobromide
GTR19203751-01Iodophenpropit dihydrobromide
GTR19237159-01Cephaeline dihydrobromide
GTR19274649-01Avizafone dihydrobromide
GTR19201230-01Immepip dihydrobromide
GTR19201229-01Immethridine dihydrobromide
GTR19154272-01Imetit dihydrobromide
GTR19177808-01BD1047 dihydrobromide
GTR19201449-01Amthamine dihydrobromide

Alternative Products

CatalogName
B6437-10Clobenpropit dihydrobromide
HY-101198-01Clobenpropit (dihydrobromide)
A22263-100Clobenpropit dihydrobromide 100mg
A22263-10Clobenpropit dihydrobromide 10mg
A22263-50Clobenpropit dihydrobromide 50mg
A22263-1Clobenpropit dihydrobromide 1mg
A22263-25Clobenpropit dihydrobromide 25mg
A22263-5Clobenpropit dihydrobromide 5mg
sc-202999Clobenpropit Dihydrobromide, VUF 9153
HY-115447Clobenpropit

Popular Products