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MAZ51

CAT: 0013-GTR19157932-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157932-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor. MAZ51 is able to block the proliferation of VEGFR-3-expressing human endothelial cells and is less potently able to induce their apoptosis. MAZ51 also inhibits the proliferation and induces the apoptosis of a variety of non-VEGFR-3-expressing tumor cell lines.In vivo, MAZ51 significantly inhibits the growth of rat mammary carcinomas. These data establish MAZ51 as a compound with antitumor properties that inhibits tumor growth directly and also indirectly by interfering with tumor-host interactions.
CAS Number
163655-37-6
Purity
>98% (HPLC)
Solubility
DMSO:3.33 mg/ml (10.59 mM; Need ultrasonic)
Smiles
CN (C) c1ccc (C=C2C (=O) Nc3ccccc23) c2ccccc12
Molecular Formula
C21H18N2O
Molecular Weight
314.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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