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PTC258

CAT: 0804-HY-148772-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148772-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PTC258 is a specific and orally active splicing modulator of Elongator complex protein 1 gene (ELP1) . PTC258 increases the expression of ELP1 in vitro and in vivo. PTC258 is well tolerated in mouse model[1].
CAS Number
2476724-74-8
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ptc258.html
Purity
99.65
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=NC(Cl)=CC(NCC2=CC=CS2)=C1S3)=C3C[C@H](C)N
Molecular Formula
C16H18ClN3S2
Molecular Weight
351.92
References & Citations
[1]Morini E, et al. Development of a novel oral treatment that rescues gait ataxia and retinal degeneration in a phenotypic mouse model of familial dysautonomia[J]. bioRxiv, 2022: 2022.11. 04.515198.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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