Products for Research Use Only
RegisterLogin

M-3M3FBS

CAT: 0013-GTR19157814-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19157814-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
M-3M3FBS is a phospholipase C (PLC) activator. m-3M3FBS stimulated a transient intracellular calcium concentration ([Ca (2+) ] (i) ) increase in neutrophils. Moreover, m-3M3FBS stimulated the formation of inositol phosphates in U937 cells, indicating that it stimulates PLC activity. The compound showed no cell-type specificity in terms of [Ca (2+) ] (i) increase in the various cell lines including leukocytes, fibroblasts, and neuronal cells, also ruled out the possible involvement of heterotrimeric G proteins in m-3M3FBS-stimulated signaling by confirming the following: 1) pertussis toxin does not inhibit m-3M3FBS-induced [Ca (2+) ] (i) increase; 2) m-3M3FBS does not stimulate cyclic AMP generation; and 3) the inhibition of G (q) by the regulator of G protein-signaling 2 does not affect the m-3M3FBS-induced [Ca (2+) ] (i) increase. m-3M3FBS stimulated PLC activity in vitro. The purified isoforms of PLC that were tested (i.e., beta2, beta3, gamma1, gamma2, and delta1) were activated by m-3M3FBS and showed no isoform specificity.
CAS Number
200933-14-8
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (291.24 mM)
Smiles
Cc1cc (C) c (c (C) c1) S (=O) (=O) Nc1cccc (c1) C (F) (F) F
Molecular Formula
C16H16F3NO2S
Molecular Weight
343.36
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Related Products

CatalogName
GTR19173961-01O-3M3FBS
GTR19216813-01O-3M3FBS
GTR19223351-01Lopinavir M-3/M-4
GTR19224614-01M-Ethoxybenzaldehyde
GTR19223115-01M-Hydroxybenzylpiperazine
GTR19223103-01M-Methylphenylacetonitrile
GTR19221520-01M-Chloramphenicol
GTR19211442-01M-COPA
GTR19280041-01Endoglycosidase M
GTR19318910ITS-M

Alternative Products

CatalogName
255742M-3M3FBS
HY-19619R-01M-3M3FBS (Standard)
sc-204142O-3M3FBS
TBI2718-50MGM-3M3FBS, Phospholipase C activator

Popular Products