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MYCi361

CAT: 0013-GTR19157793-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157793-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MYCi361 is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM) . MYCi361 is a small-molecule MYC inhibitors that inhibits the viability of MYC-dependent cancer cells including prostate cancer (MycCaP, LNCaP, and PC3), leukemia (MV4-11), lymphoma (HL-60 and P493-6), and neuroblastoma (SK-N-B2) with low-micromolar IC50 values.MYC inhibitor 361 (MYCi361), suppressed in vivo tumor growth in mice, increased tumor immune cell infiltration, upregulated PD-L1 on tumors, and sensitized tumors to anti-PD1 immunotherapy.
CAS Number
2289690-31-7
Product Name Alternative
NUCC-0196361
Purity
>98% (HPLC)
Solubility
DMSO:100 mg/mL (168.1 mM; Need ultrasonic)
Smiles
Cn1nc (cc1-c1ccc (OCc2ccc (Cl) cc2) c (-c2cc (cc (c2) C (F) (F) F) C (F) (F) F) c1O) C (F) (F) F
Molecular Formula
C26H16ClF9N2O2
Molecular Weight
594.86
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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MBS3846951-01MYCi361
A22431-5MYCi361 5mg
A22431-1MYCi361 1mg
A22431-10MYCi361 10mg

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