RABBIT ANTI IRF7 (C-TERMINAL)

RABBIT ANTI IRF7 (C-TERMINAL)

• CAS Number: 9007-83-4
• Gene Name: [IRF7]
• NCBI Gene ID: 3665
• Reactivity: Mouse, Rat
• Storage Conditions: Store at 4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
  Shelf Life: 18 months from date of despatch.
• Specificity: This item detects an epitope within the C-terminal (CT) of human interferon regulatory factor 7 (IRF7), a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production.
  
  Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.
• Other Gene Names: [IRF7; IRF7; IRF7A; IRF7B; IRF7C; IRF7H; IRF-7H; IRF-7]
• Short Name: [IRF7]
• Other Product Names: [interferon regulatory factor 7 isoform a; Interferon regulatory factor 7; interferon regulatory factor 7; IRF-7; interferon regulatory factor-7H; interferon regulatory factor 7]
• NCBI GI Number: 4758610
• NCBI Accession Number: NP_001563.2
• NCBI GB Accession Number: NM_001572.3
• Uniprot Accession Number: Q92985