MOUSE ANTI HUMAN FACTOR P

• NCBI Gene ID:

  5199

• Storage Conditions:

  Store at 4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
  Shelf Life: 18 months from date of despatch.

• Specificity:

  This item recognises human complement factor P, a 53 kDa glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections.
  
  This item does not inhibit function of complement factor P.

• Other Gene Names:

  [CFP; CFP; BFD; PFC; PFD; PROPERDIN; PFC]

• Short Name:

  [COMPLEMENT FACTOR P]

• Other Product Names:

  [properdin; Properdin; properdin; complement factor P; properdin P factor, complement; complement factor properdin; Complement factor P]

• NCBI GI Number:

  223671861

• NCBI Accession Number:

  NP_001138724.1

• NCBI GB Accession Number:

  NM_001145252.1

• Uniprot Accession Number:

  P27918

• CAS Number:

  9007-83-4