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MOUSE ANTI HUMAN FACTOR P

CAT: 0544-MBS212923-01Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0544-MBS212923-01Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
NCBI Gene ID
5199
Storage Conditions
Store at 4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Specificity
This item recognises human complement factor P, a 53 kDa glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections.

This item does not inhibit function of complement factor P.
Other Gene Names
[CFP; CFP; BFD; PFC; PFD; PROPERDIN; PFC]
Short Name
[COMPLEMENT FACTOR P]
Other Product Names
[properdin; Properdin; properdin; complement factor P; properdin P factor, complement; complement factor properdin; Complement factor P]
NCBI GI Number
223671861
NCBI Accession Number
NP_001138724.1
NCBI GB Accession Number
NM_001145252.1
Uniprot Accession Number
P27918

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