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MOUSE ANTI CHICKEN INTERFERON ALPHA

CAT: 0544-MBS212785-01Size: 0.5 mgDry Ice: NoHazardous: No
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CAT#:0544-MBS212785-01Size:0.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
NCBI Gene ID
396398
Storage Conditions
Store at 4 °C or at -20 °C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Specificity
This item recognizes chicken Interferon alpha (chIFN-alpha).
The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken.
A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.
This item does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.
Other Gene Names
[IFNA3; IFNA1; IFNA; IFNA1; IFNA2; IFNA6; IFN-alpha; IFN-gamma]
Short Name
[IFN ALPHA]
Other Product Names
[interferon type A1/A2; Interferon type A1/A2; interferon type A1/A2; IFN alpha; interferon alpha; interferon type A3; interferon-alpha; interferon]
NCBI GI Number
45382199
NCBI Accession Number
NP_990758.1
NCBI GB Accession Number
NM_205427.1
Uniprot Accession Number
P42165

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