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RSV604

CAT: 0013-GTR19157265-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157265-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RSV-604 is an inhibitor of respiratory syncytial virus (RSV) that binds to RSV nucleoprotein (Kd = 1.31 μM) . (In Vitro) :RSV604 (5 days) inhibits the growth of four laboratory strains of RSV (RSS, Long, A2 and B), with EC50s ranging from 0.5 to 0.9 μM in plaque reduction assay.RSV604 (6 days) inhibits RSV-induced HEp-2 cell death, with an EC50 of 0.86 μM.RSV604 (3 days) reduces viral antigen synthesis in RSV-infected HEp-2 cells, with an EC50 of 1.7 μM.RSV604 (1-20 μM; 7 days) dose-dependently inhibits RSV infection in human airway epithelial (HAE) cells, with no gross cytotoxicity, leakage of basolateral fluid to the apical surface, or alteration of cilium beat frequency.
CAS Number
676128-63-5
Product Name Alternative
(S) -1- (2-Fluorophenyl) -3- (2-oxo-5-phenyl-23-dihydro-1H-benzo[e][14]diazepin-3-yl) urea
Purity
>98% (HPLC)
Solubility
DMSO:195 mg/mL (502.07 mM)
Smiles
Fc1ccccc1NC (=O) N[C@H]1N=C (c2ccccc2) c2ccccc2NC1=O
Molecular Formula
C22H17FN4O2
Molecular Weight
388.39
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(S) -1- (2-fluorophenyl) -3- (2-oxo-5-phenyl-23-dihydro-1H-benzo[e][14]diazepin-3-yl) urea

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