Products for Research Use Only

Savolitinib

CAT: 0013-GTR19157082-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157082-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Savolitinib (AZD-6094) is a potent, highly selective, and orally bioavailable c-Met inhibitor with IC50s of 5 nM and 3 nM for c-Met and p-Met, respectively. Savolitinib (AZD-6094) selectively binds to and inhibits the activation of c-Met in an ATP-competitive manner, and disrupts c-Met signal transduction pathways. Antineoplastic activity.
CAS Number
1313725-88-0
Purity
>98% (HPLC)
Solubility
DMSO : 25 mg/mL (72.39 mM; Need ultrasonic) ; H2O : < 0.1 mg/mL (insoluble)
Smiles
CN1N=CC (C2=CN=C3C (N ([C@H] (C4=CN5C (C=C4) =NC=C5) C) N=N3) =N2) =C1
Molecular Formula
C??H??N?
Molecular Weight
345.36
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.