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Surfactin

CAT: 0013-GTR19156856-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19156856-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Surfactin is a potent cyclic lipopeptide biosurfactants that mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes, with anti-bacterial, anti-fungal, antimycoplasma and hemolytic effects.Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. surfactin can increase the activity of amoxicillin against avian pathogenic Escherichia coli (APEC) in vitro with antimicrobial assays such as minimum inhibitory concentrations (MIC) and fractional inhibitory concentration (FIC) .in the model of chick infection, surfactin exerted adjuvant effects with amoxicillin against APEC by lowering the numerical value of mortality and liver bacterial loads, and regulating the expression of inflammatory cytokines et al. We concluded that surfactin can act as a novel antimicrobial adjuvant with amoxicillin against AEPC infection in chicken. (In Vitro) :Surfactin C1 (0.3-10 μg/mL; 24 h) inhibits the adhesion of leukemic cell and monocyte cell to HUVEC, stimulated by LPS.Surfactin C1 (3 μg/mL; 1 h) inhibits LPS-induced expression of adhesion molecules.Surfactin C1 (3 μg/mL; 1 h) inhibits the interaction of lipid A/LBP.
CAS Number
24730-31-2
Purity
>98% (HPLC)
Solubility
DMSO:47 mg/mL (45.35mM; Need ultrasonic) ; H2O:28.25 mg/mL (27.26mM; Need ultrasonic)
Smiles
CC (C) CCCCCCCCCC1CC (=O) N[C@@H] (CCC (O) =O) C (=O) N[C@@H] (CC (C) C) C (=O) N[C@H] (CC (C) C) C (=O) N[C@@H] (C (C) C) C (=O) N[C@@H] (CC (O) =O) C (=O) N[C@H] (CC (C) C) C (=O) N[C@@H] (CC (C) C) C (=O) O1
Molecular Formula
C53H93N7O13
Molecular Weight
1036.34
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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