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Demethylwedelolactone

CAT: 0013-GTR19156594-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19156594-01Size:100 mg
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Description
Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on breast cancer cells.demethylwedelolactone (DWEL) inhibited the anchorage-independent growth and also suppressed cell motility and cell invasion of MDA-MB-231 cells.DWEL reduced the activity and expression of matrix metalloproteinases (MMPs) involved in blocking the IκB-α/NFκB and MEK/ERK signaling pathways in MDA-MB-231 cells. Furthermore, DWEL suppressed the metastasis and lung colonization of the tumor cells in the nude mice. DWEL derivatives exert anti-invasive growth effect on breast cancer cells.
CAS Number
6468-55-9
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (333.09 mM)
Smiles
O=C1C2=C (OC3=CC (O) =C (O) C=C32) C4=C (O) C=C (O) C=C4O1
Molecular Formula
C15H8O7
Molecular Weight
300.22
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
BA8337-5Demethylwedelolactone
TCC24080-01Demethylwedelolactone sulfate
HY-N2028A-01Demethylwedelolactone (Sulfate)
BD300071Demethylwedelolactone - Bio-X TM

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