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AZ7550

CAT: 0013-GTR19156702-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19156702-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZ7550 (Compound 28) appeares to offer a broadly similar potency and selectivity profile to the parent compound AZD9291. AZ7550 inhibits double mutant (DM) cell line H1975, activating mutant (AM) cell line PC9, and wild type (WT) cell line LoVo with IC50s of 45, 26, and 786 nM, respectively. AZ7550 inhibits DM antiproliferative cell line H1975, AM antiproliferative cell line PC9, and WT antiproliferative cell line Calu3 with GI50s of 19, 15, and 537 nM, respectively.
CAS Number
1421373-99-0
Purity
>98% (HPLC)
Solubility
Soluble in DMSO
Smiles
CNCCN (C) c1cc (OC) c (Nc2nccc (n2) c3cn (C) c4ccccc34) cc1NC (=O) C=C
Molecular Formula
C??H??N?O?
Molecular Weight
485.58
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Propenamide, N- (4-methoxy-5- ((4- (1-methyl-1H-indol-3-yl) -2-pyrimidinyl) amino) -2- (methyl (2- (methylamino) ethyl) amino) phenyl) - InChi Key: ZROCWKZRGJYPTG-UHFFFAOYSA-N

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