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CYM50308

CAT: 0013-GTR19156230-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19156230-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM) . CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 μM and it shows 37-fold more selective for S1P4-R than S1P5-R. (In Vitro) :The disclosed lead molecule CYM50308 (Compound 24f) displays low nanomolar S1P4-R agonist activity and exquisite selectivity over the other S1P-Rs subtypes. Noteworthy, CYM50308 provides a valuable pharmacological tool to explore the effects of the S1P4-R signaling cascade and elucidate the molecular basis of the in vivo receptor function.
CAS Number
1345858-76-5
Purity
>98% (HPLC)
Solubility
DMSO:12 mg/mL (29.60 mM; Need ultrasonic)
Smiles
O=C1N (C) /C (S/C1=C\C2=C (C) N (C3=CC=C (F) C=C3F) C (C) =C2) =N/CCOC
Molecular Formula
C20H21F2N3O2S
Molecular Weight
405.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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A22072-500CYM50308 500mg
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