Products for Research Use Only

TX1-85-1

CAT: 0013-GTR19156017-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19156017-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling. TX1-85-1 is an irreversible Her3 inhibitor (IC50: 23 nM) . TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3.
CAS Number
1603845-32-4
Purity
>98% (HPLC)
Solubility
DMSO:3.85 mg/mL (6.63 mM; Need ultrasonic)
Smiles
CC (N1CCN (C2CCC (N3N=C (C4=CC (NC (C=C) =O) =C (OC5=CC=CC=C5) C=C4) C6=C3N=CN=C6N) CC2) CC1) =O
Molecular Formula
C32H36N8O3
Molecular Weight
580.68
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.