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Solabegron

CAT: 0013-GTR19155762-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19155762-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Solabegron is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR (EC50 : 22 nM) . It is used for treatment of overactive bladder and irritable bowel syndrome. (In Vivo) :Solabegron (GW427353) at 3 mg/kg i.v. evokes an increase in micturition volume threshold that prevented the acetic acid-evoked decreases in dogs. The low dose (1 mg/kg) shows no significant activity.
CAS Number
252920-94-8
Product Name Alternative
GW 427353
Purity
>98% (HPLC)
Solubility
DMSO:250 mg/mL (608.44 mM; Need ultrasonic)
Smiles
C1=CC (=CC (=C1) C (=O) O) C2=CC (=CC=C2) NCCNC[C@@H] (C3=CC (=CC=C3) Cl) O
Molecular Formula
C23H23ClN2O3
Molecular Weight
410.89
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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