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Danicamtiv

CAT: 0013-GTR19155595-02Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19155595-02Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Danicamtiv is an inotropic agent and it also is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency.
CAS Number
1970972-74-7
Product Name Alternative
MYK-491 | SAR 440181
Purity
>98% (HPLC)
Solubility
DMSO:50mg/ml (114.83mM; Need ultrasonic)
Smiles
C[C@@] (C (CC1) CCN1C (Nc1nocc1) =O) (F) S (c1cn (C) nc1C (F) F) (=O) =O
Molecular Formula
C16H20F3N5O4S
Molecular Weight
435.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Chemical Information

Danicamtiv

Danicamtiv is under investigation in clinical trial NCT04572893 (Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants or Other Causalities).

CAS Number1970972-74-7
PubChem CID122424426
IUPAC Name4-[(1R)-1-[3-(difluoromethyl)-1-methylpyrazol-4-yl]sulfonyl-1-fluoroethyl]-N-(1,2-oxazol-3-yl)piperidine-1-carboxamide
Molecular FormulaC16H20F3N5O4S
Molecular Weight435.4
XLogP1.2
Topological Polar Surface Area119
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Heavy Atom Count29
Formal Charge0
Complexity701
SMILES
C[C@@](C1CCN(CC1)C(=O)NC2=NOC=C2)(F)S(=O)(=O)C3=CN(N=C3C(F)F)C
InChI
InChI=1S/C16H20F3N5O4S/c1-16(19,29(26,27)11-9-23(2)21-13(11)14(17)18)10-3-6-24(7-4-10)15(25)20-12-5-8-28-22-12/h5,8-10,14H,3-4,6-7H2,1-2H3,(H,20,22,25)/t16-/m1/s1
InChIKey
NREKKBAMVWQRES-MRXNPFEDSA-N
Chemical Structure
2D Structure
2D structure of Danicamtiv
CAS: 1970972-74-7
CID: 122424426
Formula: C16H20F3N5O4S
MW: 435.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight435.4
XLogP31.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Exact Mass435.11880980
Monoisotopic Mass435.11880980
Topological Polar Surface Area119 Ų
Heavy Atom Count29
Formal Charge0
Complexity701
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

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MBS3613546-01Danicamtiv
HY-109128S1Danicamtiv-d3
HY-109128SDanicamtiv-d6
HY-109128S2Danicamtiv-d3-1
C14563-5mgDanicamtiv (MYK-491)

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