Danicamtiv-d3

• Description :

  Danicamtiv-d3 (MYK-491-d3) is a deuterated labeled Danicamtiv (HY-109128) . Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency[1].

• Product Name Alternative :

  MYK-491-d3

• UNSPSC :

  12352005

• Target :

  Isotope-Labeled Compounds; Myosin

• Related Pathways :

  Cytoskeleton; Others

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O=S([C@@](C1CCN(CC1)C(NC2=NOC=C2)=O)(C)F)(C3=CN(N=C3C(F)F)C([2H])([2H])[2H])=O

• Molecular Formula :

  C16H17D3F3N5O4S

• Molecular Weight :

  438.44

• References & Citations :

  [1]Sarah Fernandes, et al. Abstract 15707: MYK-491, a Novel Small-Molecule Cardiac Myosin Activator Increases Cardiac Systolic Function and Preserves Mechanical Efficiency: Pre-Clinical in vivo and in vitro Evidence. Circulation. 2019;140:A15707.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [2925925-82-0]