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MPP+ iodide

CAT: 0013-GTR19155231-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19155231-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) externalization in dopaminergic (DA) neurons, but internalization of serotonin transporter (SERT) in serotonergic (5-HT) neurons. MPP+ induces autophagic cell death in SH-SY5Y cells.
CAS Number
36913-39-0
Purity
>98% (HPLC)
Solubility
DMSO:62.5 mg/mL (210.34 mM; Need ultrasonic) ; Water:100 mg/mL (336.54 mM; Need ultrasonic)
Smiles
C[n+] (cc1) ccc1-c1ccccc1.[I-]
Molecular Formula
C12H12IN
Molecular Weight
297.13
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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