p53DINP1 Polyclonal Antibody

This antibody recognizes human, mouse, and rat p53DINP1 (p53- Dependent Damage-Inducible Nuclear Protein 1), a p53 inducible gene. A p53DINP1 antisense oligonucleotide inhibits, and overexpression of p53DINP1 enhances, Ser46 phosphorylation of p53, induction of p53AIP1, and cell death induced by DNA double-strand breaks. The p53DINP1 gene encodes two proteins of 27 and 18 kD designated p53DINP1- alpha and p53DINP1- beta . p53DINP1 is expressed in many tissues and is induced by stress agents.
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