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Chk2 (NT) Polyclonal Antibody

CAT: 0544-MBS194194-01Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0544-MBS194194-01Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
NCBI Gene ID
11200
Storage Conditions
This antibody is stable for at least one (1) year at -20 °C. Avoid multiple freeze-thaw cycles.
Specificity
Chk2 (NT) [This rabbit antibody recognizes an epitope of aa 2-18 at the N-terminus of human, mouse, and rat Chk2 (Checkpoint Kinase 2).]
This antibody recognizes an epitope at the N-terminus of human, mouse, and rat Chk2 (Checkpoint Kinase 2). In response to DNA damage, ATM phosphorylates and activates Chk2 which in turn directly phosphorylates and activates p53. Chk2 also phosphorylates and activates BRCA1, the product of a tumor suppressor gene that is often mutated in breast and ovarian cancer.
Other Gene Names
[CHEK2; CHEK2; CDS1; CHK2; LFS2; RAD53; HuCds1; PP1425; CHK2; RAD53]
Short Name
[Chk2 (NT)]
Other Product Names
[CHK2; Serine/threonine-protein kinase Chk2; serine/threonine-protein kinase Chk2; OTTHUMP00000198969; OTTHUMP00000198970; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; protein kinase CHK2; checkpoint-like protein CHK2; CHK2 checkpoint homolog (S. pombe); Cds1]
NCBI GI Number
11034732
Uniprot Accession Number
O96017

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