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Actinonin

CAT: 0013-GTR19154274-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19154274-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Actinonin ((-) -Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities.
CAS Number
13434-13-4
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Leucyl aminopeptidase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml) .
Smiles
CCCCCC (CC (=O) NO) C (=O) NC (C (C) C) C (=O) N1C (CO) CCC1
Molecular Formula
C19H36N3O5
Molecular Weight
385.51
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3-[[1-[-2-Hydroxymethyl) -1-pyrrolidinyl) carbonyl]-2-methylpropyl]carbamoyl]-octanohydroxamic acid

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