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MMV019313

CAT: 0013-GTR19154166Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19154166Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MMV019313 (MMV 019313, MMV-019313) is a potent, specific malaria bifunctional farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS) inhibitor with IC50 of 330 nM; shows no activity against human FPPS or GGPPS (>200 uM) ; exhibits distinct modes of inhibition compared with bisphosphonates, inhibits P. falciparum growth with EC50 of 268 nM, overexpression and an S228T variant of PfFPPS/GGPPS confer resistance to MMV 019313.
CAS Number
902630-14-2
Purity
>98%
Smiles
N (C) 1C2=C (C=CC=C2) C2SC (C (NCCCN3CCCCCC3) =O) =CC=2C1=O
Molecular Formula
C22H27N3O2S
Molecular Weight
397.537
Notes
For research use only.

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