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S-BAY-8040

CAT: 0013-GTR19154153Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19154153Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S isomer of BAY-8040.Bay-8040 is a potent, selective human neutrophil elastase (HNE) inhibitor with IC50 of 28 nM; displays no significant inhibition toward 68 other pharmacologically relevant targets (>10 uM), and a panel of related serine proteases; shows in vivo efficacy with regard to decreasing cardiac remodeling and amelioration of cardiac function in monocrotaline-induced rat model for pulmonary arterial hypertension.
Purity
> 98%, Standard References
Smiles
C (C1C=CC ([C@H]2NC (=O) N (C3C=C (C (F) (F) F) C=CC=3) C3=C2C (NN (C3) C) =O) =CC=1) #N
Molecular Formula
C21H16F3N5O2
Molecular Weight
427.38
Notes
For research use only.

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