Thalidomide-5-NH2-CH2-COOH

CAT:

804-HY-46531-03

Size:

25 mg

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CAS Number: 2412056-27-8
UNSPSC Description: Thalidomide-5-NH2-CH2-COOH (compound 114) is a potent and selective inhibitor of tropomyosin receptor kinase (trk). Thalidomide-5-NH2-CH2-COOH is a ligand of E3 ligase. Thalidomide-5-NH2-CH2-COOH has the potential for researching one or more diseases (extracted from patent WO2021170109A1)[1].
Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: Apoptosis;Autophagy;PROTAC
Applications: COVID-19-immunoregulation
Field of Research: Cancer; Inflammation/Immunology
Assay Protocol: https://www.medchemexpress.com/thalidomide-5-nh2-ch2-cooh.html
Purity: 96.03
Solubility: DMSO : 33.33 mg/mL (ultrasonic)
Smiles: O=C1N(C2CCC(NC2=O)=O)C(C3=C1C=C(NCC(O)=O)C=C3)=O
Molecular Weight: 331.284
References & Citations: [1]Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. Patent WO2021170109A1.
Shipping Conditions: Room Temperature
Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information: No Development Reported

Cat	Name
HY-46531-01	Thalidomide-5-NH2-CH2-COOH
HY-46531-04	Thalidomide-5-NH2-CH2-COOH
HY-46531-03	Thalidomide-5-NH2-CH2-COOH
HY-46531-02	Thalidomide-5-NH2-CH2-COOH
HY-W584518-01	Thalidomide-5-O-CH2-COOH
HY-W584518-05	Thalidomide-5-O-CH2-COOH
HY-W584518-04	Thalidomide-5-O-CH2-COOH
HY-W584518-03	Thalidomide-5-O-CH2-COOH
HY-W584518-02	Thalidomide-5-O-CH2-COOH
HY-W129872-03	Thalidomide-5-CH2-NH2 (hydrochloride)

Cat	Name
T40019-1mg	Thalidomide-5-NH2-CH2-COOH
T40019-5mg	Thalidomide-5-NH2-CH2-COOH
T40019-50mg	Thalidomide-5-NH2-CH2-COOH
MBS5785626-01	Thalidomide-5-NH2-CH2-COOH
T40019-10mg	Thalidomide-5-NH2-CH2-COOH
MBS5785626-02	Thalidomide-5-NH2-CH2-COOH
MBS5785626-03	Thalidomide-5-NH2-CH2-COOH
T40019-1g	Thalidomide-5-NH2-CH2-COOH
T38408-10mg	Thalidomide-5-CH2-NH2 hydrochloride
MBS5799068	Thalidomide-5-CH2-NH2 hydrochloride