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JNJ-42153605

CAT: 0013-GTR19160880-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19160880-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JNJ-42153605 is a potent and selective mGlu2 receptor PAM with an acceptable pharmacokinetic profile in rodent and nonrodent species. JNJ-42153605 showed centrally mediated in vivo effectivity in models sensitive to mGlu2 receptor modulation such as sleep wake electroencephalogram (sw-EEG) in rats,34 showing suppressed REM sleep during the first 4 h after oral administration of a 3 mg/kg dose.
CAS Number
1254977-87-1
Product Name Alternative
JNJ-42153605 | JNJ 42153605 | JNJ42153605
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 16.67 mg/mL (41.63 mM)
Smiles
C12c (c (ccn1c (nn2) CC1CC1) N1CCC (CC1) c1ccccc1) C (F) (F) F
Molecular Formula
C22H23F3N4
Molecular Weight
400.45
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3- (Cyclopropylmethyl) -7- (4-phenyl-1-piperidinyl) -8- (trifluoromethyl) [1,2,4]triazolo[4,3-a]pyridine

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A14330-2JNJ 42153605 2mg
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A14330-5JNJ 42153605 5mg
A14330-1JNJ 42153605 1mg
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A14330-10JNJ 42153605 10mg

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