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NS-2028

CAT: 0013-GTR19155568-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19155568-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity) . It is commonly used in the research of nitric oxide signaling pathways. NS-2028 inhibits soluble Guanylyl Cyclase activity in homogenates of mouse cerebellum and neuronal NO synthase (IC50: 17 nM and 20 nM) . NS-2028 inhibits 3-morpholino-sydnonimine (SIN-1) -elicited formation of cyclic GMP in human cultured umbilical vein endothelial cells (IC50: 30 nM) . NS-2028 inhibits NO-dependent relaxant responses in non-vascular smooth muscle completely (1 μM) . NS-2028 decreases vascular endothelial growth factor-induced angiogenesis and permeability.
CAS Number
204326-43-2
Purity
>98% (HPLC)
Solubility
DMSO: 250 mg/mL (929.20 mM; Need ultrasonic)
Smiles
O=C1ON=C2COC3=CC=C (Br) C=C3N21
Molecular Formula
C9H5BrN2O3
Molecular Weight
269.05
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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Alternative Products

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MBS3846070-01NS-2028
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A21643-50NS-2028 50mg
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A21643-100NS-2028 100mg
A21643-25NS-2028 25mg
A21643-10NS-2028 10mg
A21643-200NS-2028 200mg
A21643-1NS-2028 1mg

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