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MCAAD-3

CAT: 0804-HY-156842-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-156842-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MCAAD-3 is a near-infrared Aβ imaging probe with blood-brain barrier penetrability. MCAAD-3 has a strong affinity for Aβ polymers (Ki >106 nM) and can label Aβ plaques in the brains of transgenic mice[1].
CAS Number
1625629-51-7
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mcaad-3.html
Purity
96.12
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN(C1=CC=C(C=C1)/C=C/C=C/C=C(C#N)/C(OC)=O)C
Molecular Formula
C17H18N2O2
Molecular Weight
282.34
References & Citations
[1]Fu H, et al. Evaluation of molecules based on the electron donor-acceptor architecture as near-infrared β-amyloidal-targeting probes. Chem Commun (Camb) . 2014 Oct 14;50 (80) :11875-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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