MC-Val-Cit-PAB (GMP)

• UNSPSC Description:

  MC-Val-Cit-PAB GMP is a GMP grade MC-Val-Cit-PAB (HY-78738). MC-Val-Cit-PAB is an intermediate in the synthesis of VcMMAE (HY-15575), which is a Drug-Linker Conjugates for ADC. Monomethyl auristatin E can be used to inhibit Microtubule/Tubulin as ADC Cytotoxin.

• Target Antigen:

  ADC Linker

• Type:

  GMP Small Molecules

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mc-val-cit-pab-gmp.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(CO)C=C1)=O)=O)NC(CCCCCN2C(C=CC2=O)=O)=O

• Molecular Weight:

  572.65

• References & Citations:

  [1]Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  159857-80-4